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I have made a MSI bundle for my customer's installer where WinCC OA is included as an ExePackage.
When the resulting bundle setup runs a fresh install on a fresh virtual machine, the error code 0x80070643 is returned, as soon as the WinCC OA Base package is about to be installed.
Prerequisites install nicely. Patching an existing installation works also.

From Bundle.wxs:
<ExePackage Id="Package_WinCCOA"
SourceFile="WinCC_OA_3.21.3_Setup_x64.exe"
InstallArguments="/passive
INSTALLADDONS=0
INSTALLAPICPP=0
INSTALLAPICSHARP=0
INSTALLAPPLICATIONS=0
INSTALLBASESERVER=1
INSTALLBASEUI=1
INSTALLBASEUISHORTCUTS=1
INSTALLDESKTOPUISHORTCUTS=0
INSTALLDIR=&quot;C:/Siemens/Automation/WinCC_OA/3.21&quot;
INSTALLHELPDE=1
INSTALLHELPEN=1
INSTALLINFLUXSERVER=0
INSTALLITCSERVER=0
INSTALLJAVASCRIPTENV=0
INSTALLOPCDA=0
INSTALLPOSTGRESQLCLIENT=1
INSTALLPOSTGRESQLSERVER=1
INSTALLPROFISAFE=0
INSTALLS7PLUS=0
INSTALLSPECIALFUNCTIONS=1
INSTALLVIDEO=0
INSTALLVIMACC=0
INSTALLX86COMPONENTS=1
PROJECTDIR=&quot;C:/WinCC_OA_Proj&quot;
SUPPRESSREBOOT=1"
DetectCondition="true"
Permanent="yes"
Vital="yes">

<!-- treat 0x20000001 (decimal 536870913) as success (same version installed) -->
<ExitCode Value="536870913" Behavior="success" />
<!-- treat 0x20000002 (decimal 536870914) as success (newer version installed) -->
<ExitCode Value="536870914" Behavior="success" />
</ExePackage>

Logfile:
[0540:0CAC][2026-07-20T13:40:38]i301: Applying execute package: Base, action: Install, path: C:\ProgramData\Package Cache\{27DC2DB2-82A3-9C56-AAC6-91FBCCBB0DE6}v3.21.003.0\BA\Base.msi, arguments: ' INSTALLDIR="C:/Siemens/Automation/WinCC_OA/3.21" PROJECTDIR="C:/WinCC_OA_Proj" TRANSFORMS="" ALLUSERS="1" ARPSYSTEMCOMPONENT="1" MSIFASTINSTALL="7" BURNMSIINSTALL=1 REINSTALLMODE="muse" REBOOT=ReallySuppress'
[0540:0CAC][2026-07-20T13:40:41]e000: Error 0x80070643: Failed to install MSI package.
[0540:0CAC][2026-07-20T13:40:41]e000: Error 0x80070643: Failed to execute MSI package.
[1EC0:02F4][2026-07-20T13:40:41]e000: Error 0x80070643: Failed to configure per-machine MSI package.
[1EC0:02F4][2026-07-20T13:40:41]i319: Applied execute package: Base, result: 0x80070643, restart: None
[1EC0:02F4][2026-07-20T13:40:41]e000: Error 0x80070643: Failed to execute MSI package.